COVID‐19 and its Severity in Bariatric Surgery‐Operated Patients

Etienne Charpentier , Alban Redheuil , Olivier Bourron , Samia Boussouar , Olivier Lucidarme , Mohamed Zarai , Nadjia Kachenoura , Khaoula Bouazizi , Joe-Elie Salem , Guillaume Hekimian , Matthieu Kerneis , Zahir Amoura , Yves Allenbach , Stephane Hatem , Anne-Caroline Jeannin , Fabrizio Andreelli (1) , Franck Phan , Romain Tilmont , Romain Chenu , Louise Meyfroit , Nicoletta Pasi , Schahrazed Larbi-Messaoud , Suzanne Laroche , Cécile Ciangura (2, 3) , Marc Popelier , Sophie Jacqueminet , Marine Halbron , Agnès Hartemann

1 Nutriomics - Nutrition et obésités: approches systémiques (UMR-S 1269)
2 CHU Pitié-Salpêtrière [AP-HP]
3 CRNH-IDF - Centre de Recherche en Nutrition Humaine d'Ile-de-France

Objective: Obesity is a major risk factor for severe forms of coronavirus disease (COVID-19), but little is known about the post-bariatric surgery (BS) setting. The prevalence of likely COVID-19 and its risk factors in patients followed up after BS was assessed. Methods: A total of 738 patients who underwent BS and were followed up at a university medical center were surveyed. A retrospective comparison of characteristics at baseline, 1 year after BS, and at the time of lockdown was performed between patients with COVID-19-likely events (CL) based on a combination of reported symptoms and those for whom COVID-19 was unlikely. Results: CL occurred in 62 (8.4%) patients, among whom 4 (6.4%) had a severe form requiring hospitalization and 1 (1.6%) died. The CL group had a higher proportion of persistent type 2 diabetes (T2D) at last follow-up (36.2% vs. 20.3%, P = 0.01). BMI at the time of lockdown was lower in the CL group (30.2 ± 5.1 vs. 32.8 ± 6.5 kg/m2 ; P < 0.01) with higher percent weight loss since BS in the CL group. Severe forms of COVID-19 requiring hospitalization were associated with persistent T2D at the last follow-up visit. Conclusions: In BS patients, CL were associated with persistent T2D and lower BMI.

Domaines: Sciences du Vivant [q-bio]

Etienne Charpentier, Alban Redheuil, Olivier Bourron, Samia Boussouar, Olivier Lucidarme, et al.. COVID‐19 and its Severity in Bariatric Surgery‐Operated Patients. Obesity, 2020, 21 (1), pp.294. ⟨10.1002/oby.23026⟩. ⟨hal-03080068⟩